ELISA

Soluble Growth-Stimulating Expressed Gene 2 Protein (sST2)

-Heart Fibrosis-Specific Marker

Diagnostic reagent for quantitative in vitro determination of Soluble growth stimulating gene 2 protein (sST2) in human serum on photometric systems

Clinical Significance

● Specific indicators of myocardial fibrosis

● Predicts acute heart failure morbidity and mortality in patients with dyspnea

● Acute and chronic heart failure risk stratification

● Acute heart failure mortality monitoring

● Chronic heart failure mortality assessment

● Combined detection with natriuretic peptide to improve the value of risk assessment

Indicator Advantage

Specificity: specific indicators of myocardial fibrosis

Independence: The risk of heart failure can be independently assessed, and a single threshold (38ng/ml) is easy to interpret

Stability: The measured value of the sample is stable and accurate, and the interference factor is small

Guide Recommendation

Chinese Heart Failure Diagnosis and Treatment Guidelines 2018

Indicators such as soluble ST2 (class Ila, level B) reflecting myocardial fibrosis may provide additional information in risk stratification of chronic heart failure.

Indicators such as soluble ST2, which reflect myocardial fibrosis, may provide additional information in risk stratification of acute heart failure (Class IIb, Level A).

Applicable Departments

Department of Cardiology Laboratory Infectious Diseases

Chest Pain Center

Emergency Department

Respiratory department

Heart Failure Center